Independent Biotech Advisory
A leaner way to build a biotech.
David Craig helps founders, CEOs, and boards run capital efficient drug-development companies the virtual-biotech model, put to work. Fractional leadership, fundraising and Business Development strategy, and the operating playbook behind The New Rules of Biotech
Twenty-five years inside drug development, now on your side of the table.
Operator experience across large pharma and clinical-stage companies brought to the founders building what’s next.
David Craig
Founder and Principal
I've raised the money, built the teams, run the programs, and advanced candidate therapeutics into clinic or commercialization so I can help you do it without the false starts.
Across Amgen, Gilead, and Portola, and as a founder-CEO since, I've worked every seam of the drug-development stack: preclinical strategy, Chemistry, Manufacturing and Control (CMC) and Investigational New Drug (IND) enabling programs, fundraising, and business development. D. Craig Consulting brings that experience to emerging biotechs as fractional leadership and hands-on advisory.
The through line is the virtual biotech a disciplined, outsourced network operating model that gets more program per dollar. It's the subject of my writing and the way I help clients work.
Focus
Neuromuscular & rare disease · small molecules and biologics
Engagements
Retained by the quarter or the project. Every engagement is scoped to a decision you need to reach.
Fractional and interim leadership
Step in as CEO or operating lead to get a program funded, staffed, and moving with a clean handoff when it's built.
Fundraising and business development
Positioning, materials, and investor and partner strategy from seed through Series A and BD deals.
Virtual-biotech operating design
Stand up a lean, outsourced Chemistry, Manufacturing and Control (CMC) and clinical network. Real velocity without building fixed infrastructure.
Now available
The New Rules of Biotech
A Founder’s Guide to Building Great Companies
$39.95 hardcover · $24.99 paperback · $14.99 Kindle
- The Virtual Biotech Playbook
Resources
Working models and checklists from real programs. Free to download take them apart and make them yours.
R-001
Cap Table, Dilution, and Exempt Offering Model
Cap table and dilution model for seed through Series B rounds, including exempt
offering thresholds and pro-forma ownership logic.
139 KB
AUG 2026
R-002
Fundraise and Investor Tracker
Track outreach, stage, and follow-ups across an active raise.
62 KB
Jun 2026
R-003
IND-Readiness Checklist
Gap-check your program against IND-enabling requirements.
31 KB
Aug 2026
R-004
Virtual-Biotech Operating Model
Headcount, vendor, and burn model for the outsourced-network approach.
36 KB
Aug 2026
R-005
Term-Sheet Comparison Worksheet
Line up preferred terms side by side before you negotiate.
62 KB
Jun 2026
R-001
Cap Table & Dilution Model
Plan rounds, option pool, and dilution from seed to Series A.
62 KB
Jun 2026
R-002
Fundraise & Investor Tracker
Track outreach, stage, and follow-ups across an active raise.
62 KB
Jun 2026
Term-Sheet Comparison Worksheet
Line up preferred terms side by side before you negotiate.
62 KB
Jun 2026
R-003
IND-Readiness Checklist
Gap-check your program against IND-enabling requirements.
62 KB
Jun 2026
Start a conversation
Have a program that needs senior help?
Tell me where you are and what you're deciding. I'll tell you honestly whether I can move the needle.